For clinical reference only — does not replace local trust guidelines or clinical judgement.
‹ Blood Results
Blood Results

Raised Creatinine

Raised Creatinine

Severity
Range
  • Mild
    Cr 1.5–1.9× baseline (Stage 1 AKI)
  • Moderate
    Cr 2.0–2.9× baseline (Stage 2 AKI)
  • Severe
    Cr ≥ 3× baseline or anuric (Stage 3 AKI)
❤️

Cardiovascular (pre-renal) Causes

Hypovolaemia — haemorrhage, dehydration, D&VCardiac failure / cardiogenic shockSepsis / distributive shockRenal artery stenosis
🫘

Renal (intrinsic) Causes

Acute tubular necrosis (ischaemia, contrast, rhabdo)Acute interstitial nephritis (PPI, NSAID, antibiotic)Glomerulonephritis, vasculitis (ANCA, anti-GBM)Rhabdomyolysis, tumour lysis
🚽

Urological (post-renal) Causes

Prostatic enlargement, urinary retentionBlocked / displaced catheterPelvic malignancy, bilateral stonesRetroperitoneal fibrosis
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Drugs (nephrotoxic) Causes

ACEi, ARBNSAIDsAminoglycosides (gentamicin), vancomycinIV contrast, amphotericinTacrolimus, ciclosporin, methotrexate
🧬

Systemic / inflammatory Causes

Vasculitis, SLEMyeloma (always check in older patients with AKI)Hepatorenal syndromeHUS / TTP, malignant hypertension